General Information |
|
Product |
PD-L2 Antibody BIOTIN |
Description |
BIOTIN-Conjugated Programmed cell death 1 ligand 2 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey Predicted: Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 115-165 on human Programmed cell death 1 ligand 2 protein. |
Accession # |
NCBI: NP_079515 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Molecular Function |
Receptor |
Subcellular Location |
Isoform 3 : Secreted Isoform 2 : Endomembrane system, Single-pass type I membrane protein Isoform 1 : Cell membrane, Single-pass type I membrane protein |
Expression |
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
Structure |
Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
Alternative Nomenclature |
B7 dendritic cell molecule antibody B7-DC antibody bA574F11.2 antibody Btdc antibody Butyrophilin B7 DC antibody CD 273 antibody PD 1 ligand 2 antibody PD-L2 antibody PDCD 1 ligand 2 antibody PDCD1L2 antibody Pdcd1lg2 antibody Programmed cell death 1 ligand 2 antibody Programmed death ligand 2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
PDL2-201AP | |||
|
PDL2-FITC | |||
|
P-PDL2 | |||
|
PC-PDL2 | |||
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