General Information |
|
Product |
CCR4 Antibody Antigenic Blocking Peptide |
Description |
Antigenic Blocking Peptide C-C chemokine receptor type 4 Antibody |
Verified Applications |
Immmunodepletion, Competition Assay |
Peptide Description |
Synthetic peptide |
Accession # |
NCBI: NP_005499 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Receptor for C-C type chemokines CCL17/TARC and CCL22/MDC. Functions as chemoattractant homing receptor on circulating memory lymphocytes and as coreceptor for some primary HIV-2 isolates. Can also mediate hippocampal-neuron survival. |
Molecular Function |
GPCR, Receptor, Transducer. |
Subcellular Location |
Cell membrane; Multi-pass membrane protein |
Expression |
Thymus, peripheral blood leukocytes including T-cells, CD4+ cells, basophils and in platelets. Expressed less in spleen and in monocytes. Also found in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expresseding cutaneous lymphocyte antigen. Expressed in brain and microvascular and coronary artery endothelial cells. |
Structure |
Belongs to G-protein coupled receptor 1 family. Interacts with CREB3. |
Alternative Nomenclature |
CD194 antibody ChemR13 antibody CKR4 antibody CMKBR 4 antibody HGCN 14099 antibody K5 5 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
CCR4-401AP | |||
|
CCR4-FITC | |||
|
CCR4-BIOTIN | |||
|
PC-CCR4 | |||
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