General Information |
|
Product |
DWORF Antibody BIOTIN |
Description |
BIOTIN-Conjugated Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synththetic peptide corresponding to full length Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:2,500-1:5,000 |
|
|
Uniprot # |
|
Overview |
Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulates SERCA pump activity. Enhances sarcoplasmic reticulum Ca2+ uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN). |
Molecular Function |
Sarcoplasmic reticulum membrane; Single-pass membrane protein |
Alternative Nomenclature |
Dwarf open reading frame antibody DWORF antibody Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORFSERCA regulator DWORF antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
DWORF-112AP | |||
|
DWORF-112-FITC | |||
|
P-DWORF-112 | |||
|
PC-DWORF | |||
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