General Information |
|
Product |
WDR5 Positive Control |
Description |
Western Blot Positive Control WD repeat-containing protein 5 |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
NCBI: NP_060058.2 |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. |
Molecular Function |
Chromatin regulator |
Subcellular Location |
Nucleus |
Structure |
Interacts with PAXBP1; the interaction is direct and links a WDR5-containing histone methyltransferase complex to PAX7 and PAX3. Interacts with HCFC1. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
Alternative Nomenclature |
2410008O07Rik antibody AA408785 antibody AA960360 antibody Big antibody BIG3 antibody BMP2 induced 3 kb gene protein antibody MGC114572 antibody OTTHUMP00000162494 antibody SWD3 Set1c WD40 repeat protein homolog antibody WD repeat-containing protein 5 antibody WD repeat-containing protein BIG-3 antibody WDR 5 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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WDR5-101AP | |||
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WDR5-FITC | |||
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P-WDR5 | |||
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WDR5-BIOTIN | |||
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