General Information
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Product
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Phospho-JAK1 Antibody
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Description
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Affinity Purified Phosphorylated Tyrosine-protein kinase JAK1 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 1000-1050 on human JAK1 protein. Phosphorylated 1034 & 1035 tyrosine residues.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Modification |
Phosphorylated tyrosine 1034 & 1035. |
Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P23458
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Overview
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Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).
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Molecular Function
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Kinase, Transferase, Tyrosine-protein kinase
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Expression
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Endomembrane system; Peripheral membrane protein
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Structure
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Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
Contains 1 FERM domain.
Contains 2 protein kinase domains.
Contains 1 SH2 domain.
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Alternative Nomenclature
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JAK 1
JAK 1A
JAK 1B
Janus kinase 1 (a protein tyrosine kinase)
Janus kinase 1
JTK3
Tyrosine protein kinase JAK1
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