General Information

Product

Dopamamine Receptor D1 Antibody

Description

Affinity Purified D(1A) dopamine receptor Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on mouse D(1A) dopamine receptor.

Accession #

NCBI:  NP_036678

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P18901

Overview

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

Molecular Function

angiotensin receptor binding;protein heterodimerization activity;protein phosphatase binding;ATPase binding

Subcellular Location

Cell membrane;Endoplasmic reticulum Membrane

Expression

Brain, in the striatum, the nucleus accumbens, and the olfactory tubercle.

Structure

Belongs to the G-protein coupled receptor 1 family has a Transmembrane helix domain

Alternative Nomenclature

D(1A) dopamine receptor antibody

D1A dopamine receptor antibody

DADR antibody

Dopamine D1 receptor antibody

DRD1A antibody

General Information

Product

Dopamamine Receptor D1 Antibody

Description

Affinity Purified D(1A) dopamine receptor Antibody Mid Region

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 on mouse D(1A) dopamine receptor.

Accession #

NCBI:  NP_036678

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid Region

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P18901

Overview

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

Molecular Function

angiotensin receptor binding;protein heterodimerization activity;protein phosphatase binding;ATPase binding

Subcellular Location

Cell membrane;Endoplasmic reticulum Membrane

Expression

Brain, in the striatum, the nucleus accumbens, and the olfactory tubercle.

Structure

Belongs to the G-protein coupled receptor 1 family has a Transmembrane helix domain

Alternative Nomenclature

D(1A) dopamine receptor antibody

D1A dopamine receptor antibody

DADR antibody

Dopamine D1 receptor antibody

DRD1A antibody

General Information

Product

Dopamamine Receptor D1 Antibody

Description

Affinity Purified D(1A) dopamine receptor Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on mouse D(1A) dopamine receptor.

Accession #

NCBI:  NP_036678

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P18901

Overview

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

Molecular Function

angiotensin receptor binding;protein heterodimerization activity;protein phosphatase binding;ATPase binding

Subcellular Location

Cell membrane;Endoplasmic reticulum Membrane

Expression

Brain, in the striatum, the nucleus accumbens, and the olfactory tubercle.

Structure

Belongs to the G-protein coupled receptor 1 family has a Transmembrane helix domain

Alternative Nomenclature

D(1A) dopamine receptor antibody

D1A dopamine receptor antibody

DADR antibody

Dopamine D1 receptor antibody

DRD1A antibody

General Information

Product

Dopamamine Receptor D1 Antibody

Description

Affinity Purified D-1 dopamine receptor Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human D-1 dopamine receptor protein.

Accession #

GenBank:  CAA41734

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P21728

Overview

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

Molecular Function

angiotensin receptor binding;protein heterodimerization activity;protein phosphatase binding;ATPase binding

Subcellular Location

Cell membrane;Endoplasmic reticulum Membrane

Expression

Brain, in the striatum, the nucleus accumbens, and the olfactory tubercle.

Structure

Belongs to the G-protein coupled receptor 1 family has a Transmembrane helix domain

Alternative Nomenclature

D(1A) dopamine receptor antibody

D1A dopamine receptor antibody

DADR antibody

Dopamine D1 receptor antibody

DRD1A antibody

General Information

Product

Dopamamine Receptor D1 Antibody

Description

Affinity Purified D-1 dopamine receptor Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 290-340 on human D-1 dopamine receptor protein.

Accession #

GenBank:  CAA41734

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P21728

Overview

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

Molecular Function

angiotensin receptor binding;protein heterodimerization activity;protein phosphatase binding;ATPase binding

Subcellular Location

Cell membrane;Endoplasmic reticulum Membrane

Expression

Brain, in the striatum, the nucleus accumbens, and the olfactory tubercle.

Structure

Belongs to the G-protein coupled receptor 1 family has a Transmembrane helix domain

Alternative Nomenclature

D(1A) dopamine receptor antibody

D1A dopamine receptor antibody

DADR antibody

Dopamine D1 receptor antibody

DRD1A antibody

General Information

Product

GTP cyclohydrolase 1 Antibody

Description

Affinity Purified GTP cyclohydrolase 1 Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 25-75 on mouse GTPCHI protein.

Accession #

GeneBank: AAH05643

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.73-1.01 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q05915

Overview

Positively regulates nitric oxide synthesis in endothelial cells.  Invovled in dopamine synthesis and pain sensitivity and persistence.

Molecular Function

Cofactor biosynthesis; GTP binding; Coenzyme binding; Calcium ion binding

Subcellular Location

Cytoplasm; Nucleus

Structure

Toroid-shaped homodecamer.  Composed of two pentamers of five dimers.

Alternative Nomenclature

dystonia 14 antibody

DYT 5 antibody

DYT14 antibody

DYT5a antibody

GCH antibody

GTP CH 1 antibody

GTP cyclohydrolase 1 (dopa responsive dystonia) antibody

Guanosine 5' triphosphate cyclohydrolase I antibody

HPABH4B antibody

General Information

Product

GTP cyclohydrolase 1 Antibody Affinity Purified

Description

Affinity Purified GTP cyclohydrolase 1 Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid region 1-50 on GTPCHI protein.

Accession #

GeneBank: AAH05643

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.98 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q05915

Overview

Positively regulates nitric oxide synthesis in endothelial cells.  Invovled in dopamine synthesis and pain sensitivity and persistence.

Molecular Function

Cofactor biosynthesis; GTP binding; Coenzyme binding; Calcium ion binding

Subcellular Location

Cytoplasm; Nucleus

Structure

Toroid-shaped homodecamer.  Composed of two pentamers of five dimers.

Alternative Nomenclature

dystonia 14 antibody

DYT 5 antibody

DYT14 antibody

DYT5a antibody

GCH antibody

GTP CH 1 antibody

GTP cyclohydrolase 1 (dopa responsive dystonia) antibody

Guanosine 5' triphosphate cyclohydrolase I antibody

HPABH4B antibody

General Information

Product

D4S234E Antibody

Description

Affinity Purified Neuron-specific protein family member 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 140-190 on human Neuron-specific protein family member 1.

Accession #

NCBI:  NP_077042

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:150

Immunohistochemistry

1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P02683

Overview

clathrin light chain binding

Subcellular Location

Golgi apparatus membrane; single-pass type II membrane protein

Structure

Belongs to the NSG family.

Alternative Nomenclature

Brain neuron cytoplasmic protein 1 antibody

Brain specific mRNA b antibody

Bsmrb antibody

Neuron-specific gene family member 1 antibody

Neuron-specific protein family member 1 antibody

NSG1 antibody

PEP1 antibody

General Information

Product

NSG2 Antibody

Description

Affinity Purified Neuron-specific protein family member 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 130-171 on human Neuron-specific protein family member 2.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:150

Immunohistochemistry

1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9Y328

Overview

Clathrin light chain binding

Molecular Function

Clathrin coat assembly, Dopamine receptor signaling pathway, Endosomal transport

Subcellular Location

Cytoplasmic vessicle membrane, Golgi apparatus, Endosome

Structure

Belongs to the NSG family.

Alternative Nomenclature

HMP19 antibody

Neuron-specific protein family member 2 antibody

Nsg2 antibody

NSG2_HUMAN antibody

Protein p19 antibody

General Information

Product

CD300 Antibody

Description

Affinity Purified CMRF35-like molecule 1 / CD300LF Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 230-290 on human CMRF35-like molecule 1 / CD300LF.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:150

Immunohistochemistry

1:50-1:150

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8TDQ1

Overview

Acts as an inhibitory receptor for myeloid cells and mast cells (PubMed:15549731). Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands (PubMed:24035150). May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:22043923). Inhibits osteoclast formation. Induces macrophage cell death upon engagement.

Molecular Function

ceramide binding

interleukin-4 receptor binding

phosphatidylserine binding

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Expression

Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.

Alternative Nomenclature

CD300 antigen like family member antibody

CD300 antigen-like family member F antibody

CD300f antibody

CD300LF antibody

CLM antibody

CLM-1 antibody

CMRF35-like molecule 1 antibody

IGSF antibody

IgSF13 antibody

Immune receptor expressed on myeloid cells 1 antibody

immunoglobin superfamily member antibody

Immunoglobulin superfamily member 13 antibody

Inhibitory receptor IREM1 antibody

IREM antibody

IREM-1 antibody

Nepmucin antibody

NK inhibitory receptor antibody

NKIR antibody

TREM antibody

triggering receptors expressed on myeloid cells antibody

UNQ3105/PRO10111 antibody