ASXL1 Antibody

Product no.: ASXL1-101AP

$285.00

Description

General Information
Product	ASXL1 Antibody
Description	Affinity Purified Putative Polycomb group protein ASXL1 Antibody
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1120-1180 on mouse Putative Polycomb group protein ASXL1.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5-1.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Purification Method	Immobilized antigen affinity chromatography
Clonality	Polyclonal
Storage	-20?C for long term storage
Application Protocol
ELISA	1:50,000
Immunoprecipitation	1:200
Western Blot	1:500-1:5,000
Protein
Uniprot #	P59598
Overview	Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG) (PubMed:16606617). Acts as a coactivator of RARA and RXRA through association with NCOA1 (PubMed:16606617). Acts as a corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity (PubMed:21047783).
Molecular Function	chromatin binding DNA binding metal ion binding peroxisome proliferator activated receptor binding retinoic acid receptor binding transcription coactivator activity
Subcellular Location	Nucleus
Structure	Belongs to the Asx family.
Alternative Nomenclature	Additional sex combs like 1 (Drosophila) antibody Additional sex combs like protein 1 antibody ASXL1 antibody ASXL1_HUMAN antibody KIAA0978 antibody Putative Polycomb group protein ASXL1 antibody

Protein information supplied by UniProt.