General Information
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Product
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Cytokeratin 7 Peptide
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Description
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Antigenic Blocking Peptide keratin, type II cytoskeletal 7 Antibody Mid Region
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Verified Applications
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Immunocompetition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 101-151 on human keratin, type II cytoskeletal 7 protein.
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Accession #
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NCBI: NP_005547
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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Mid Region
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P08729.5
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Overview
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Serves to block interferon-dependent interphase and stimulates DNA synthesis. Plays a role in the translational regulation of human papillomavirus type 16 E7 mRNA.
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Molecular Function
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Structural molelcule activity; Host-virus interaction
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Subcellular Location
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Cytoplasm
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Expression
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Expressed in cultured epidermal, bronchial and mesothelial cells. Seen throughout the glandular cells at the junction of the stomac and esophagus; not present in the esophogus, colon, ectocervix and liver.
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Structure
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Heterotetramer of two type I and two type II keratins, interacts with eukaryotic translation initiator factor 3 subunit EIF3S10 , HPV16 E7, and GPER1.
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Alternative Nomenclature
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CK 7 antibody
Cytokeratin 7 antibody
K2C7 antibody
K7 antibody
Keratin 55k type ii cytoskeletal antibody
Keratin 7 antibody
KRT 7 antibody
Krt2-7 antibody
Sarcolectin antibody
SCL antibody
Type-II keratin Kb7 antibody
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