General Information
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Product
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Nogo Positive Control
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Description
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Western Blot Positive Control Reticulon-4 isoform A Antibody
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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NCBI: NP_065393.1
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9NQC3
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Overview
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Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system.
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Molecular Function
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poly(A) RNA binding
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Subcellular Location
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Endoplasmic reticulum membrane; Multi-pass membrane protein
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Expression
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Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 is widely expressed except for the liver. Isoform 3 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 is testis-specific.
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Structure
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Binds to RTN4R, interacts with Bcl-xl and Bcl-2. Isoform 2 binds to NGBR and RTN3. Isoform 2 and Isoform 3 interact with BACE1 and BACE2, interacts with RTN4IP1 and ATL1.
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Alternative Nomenclature
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1110020G17Rik antibody
AA407876 antibody
AA409940 antibody
AA960376 antibody
ASY antibody
C130026I10Rik antibody
Foocen antibody
Glut4 vesicle 20 kDa protein antibody
Human NogoA antibody
Kiaa0886 antibody
KIAA4153 antibody
MGC116054 antibody
MGC139261 antibody
mKIAA0886 antibody
mKIAA4153 antibody
My043 protein antibody
Nbla00271 antibody
Nbla10545 antibody
Neurite growth inhibitor 220 antibody
Neuroendocrine-specific protein antibody
NI-250 antibody
Nogo A antibody
NOGO antibody
Nogo B antibody
Nogo C antibody
NSP antibody
NSP CL antibody
rat N antibody
Reticulon 4 antibody
Reticulon 5 antibody
RTN X antibody
RTN4 A antibody
RTN4-B1 antibody
Vp20 antibody
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