General Information |
|
Product |
ACK1 Antibody BIOTIN |
Description |
BIOTIN-Conjugated Activated CDC42 kinase 1 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 250-300 on ACK1 protein. |
Accession # |
GenBank: L13738.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.59-0.68 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Non-receptor tyrosine-protein and serine/threonine-protein kinase implicated in cell sperading and migration, survival, growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. |
Molecular Function |
ATP binding; epidermal growth factor receptor binding; GTPase inhibitor activity; non-membrane spanning protein tyrosine kinase activity; protein serine/threonine kinase activity |
Subcellular Location |
Cell membrane; Nucleus; Endosome; Cell junction; adherens junction; Cytoplasmic vessicle membrane; Peripheral membrane protein; Clathrin-coated vessicles; Clathin coated pit |
Expression |
During progressive stages in breast and prostate cancer |
Structure |
Forms complexes with GRB2 and several receptor tyrosine kinases. Part of collagen stimulated complex. |
Alternative Nomenclature |
Acetate kinase 1 antibody Acetokinase 1 antibody ACK 1 antibody Activated Cdc42 associated kinase 1 antibody Activated CDC42 kinase 1 antibody Activated p21cdc42Hs kinase antibody p21cdc42Hs antibody TNK 2 antibody Tyrosine kinase non-receptor protein 2 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
ACK-101AP | |||
|
P-ACK1 | |||
|
ACK1-FITC | |||
|
PC-ACK1 | |||
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