General Information |
|
Product |
Eprhin Receptor A6 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Ephrin type-A receptor 6 isoform A Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 800-900 on human EphA R6 protein. |
Accession # |
NCBI: NP_001073917 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.75 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). |
Molecular Function |
ATP-binding, Nucleotide-binding |
Subcellular Location |
Membrane; Single-pass type I membrane protein |
Expression |
Expressed in brain and testis. |
Structure |
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity). |
Alternative Nomenclature |
Ehk 2 antibody EPH homology kinase 2 antibody Eph Receptor A6 antibody ephrin receptor EphA6 antibody Hek12 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
EPHAR6-601AP | |||
|
P-EPHAR6 | |||
|
EPHAR6-BIOTIN | |||
|
PC-EPHAR6 | |||
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