General Information |
|
Product |
IFI16 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Gamma-interferon-inducible protein 16 isoform 1 Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human |
Immunogen |
Synthetic peptide taken within amino acid region 140-190 on human IFI16 protein |
Accession # |
NCBI: NP_001193496.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.58-0.62 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. |
Molecular Function |
Core promoter binding, identical protein binding, transcription factor binding, double-standard DNA binding, poly(A) RNA binding |
Subcellular Location |
Nucleus, cytoplasm (Note: Cellular distribution is dependent on acetylation status of multipartite nuclear localization signal(NLS); NLS acetylation promotes cytoplasmic localization. Localizes in nucleus during human herbes simplex virus 1 infection) |
Expression |
Expressed in peripheral blood leukocytes, fibroblasts and lymphoid cells. Present in myeloid precursors (CD34+) and throughout monocyte development, but its expression is down-regulated in erythroid and polymorphonuclear precursor cells. Present in prosta |
Alternative Nomenclature |
IFI16 antibody Gamma interferon inducible protein 16 antibody Ifi204 antibody IFNGIP1 antibody interferon activated gene 204 antibody Interferon gamma inducible protein 16 antibody p204 antibody PYHIN2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-IFI16H | |||
|
IFI16H-101AP | |||
|
IFI16H-FITC | |||
|
PC-IFI16H | |||
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