Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'/ May play a role in the function or determination of a particular subset of cells in the developing embryo.
Molecular Function
DNA-Binding
Subcellular Location
Nucleus
Expression
Early expression in mesodermal and cephalic furrow. Late embryonic development expression is ectodermal, corresponding to muscle attachment sites. Also in midgut, hindgut and analpad.
Fabgennix DFosAntibody has been used in 3 Publications
Ling, Jinli, Raphaëlle Dubruille, and Patrick Emery. âKAYAK-α Modulates Circadian Transcriptional Feedback Loops in Drosophila Pacemaker Neurons.â The Journal of neuroscienceâ¯: the official journal of the Society for Neuroscience 32.47 (2012): 16959â16970. PMC3528402
Western Blot; Drosophila melanogaster
Massaro, Catherine M., Jan Pielage, and Graeme W. Davis. âMolecular Mechanisms That Enhance Synapse Stability Despite Persistent Disruption of the Spectrin/ankyrin/microtubule Cytoskeleton.âThe Journal of Cell Biology187.1 (2009): 101â117.PMC2762090
Western Blot; Drosophila melanogaster
Hartwig, Cortnie L. et al. âNormal Dendrite Growth in Drosophila Motor Neurons Requires the AP-1 Transcription Factor.â Developmental neurobiology 68.10 (2008): 1225â1242.PMC2719294
Confocal Microscopy, Immunocytochemistry, Immunofluorescence, Western Blot; Drosophila melanogaster
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