General Information |
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Product |
GADD34 Peptide |
Description |
Antigenic Blocking Peptide Growth arrest and DNA damage-inducible protein GADD34 |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein.
Sequence: PATGVFLKSWVYQPGEDTEEE |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. |
Molecular Function |
Apoptosis; Stress Response; Translation regulation |
Subcellular Location |
Endoplasmic Reticulum membrane; Peripheral membrane protein; Cytoplasmic side; Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic Side |
Expression |
induced by methyl methanesulfonate and ionizing irradiation. Apoptosis is induced by interluekin 24 in melanoma cells |
Structure |
belongs to PPP1R15 family. |
Alternative Nomenclature |
Apoptosis associated protein antibody GADD 34 antibody Growth arrest and DNA-damage-inducible 34 antibody Myeloid differentiation primary response protein MyD116 homolog antibody PPP1R15A antibody Protein phosphatase 1 regulatory (inhibitor) subunit 15A antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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GADD34-101AP | |||
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GADD34-FITC | |||
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GADD34-BIOTIN | |||
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PC-GADD34 | |||
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