General Information |
|
Product |
EFEMP1 Antibody FITC |
Description |
FITC-Conjugated EGF-containing fibulin-like extracellular matrix protein 1 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic cyclic peptide corresponding to N terminal amino acids 25-42 of Human EFEMP1, peptide was covalently modified.
Sequence: TYTQCTDGYEWDPVRQQC |
Accession # |
NCBI: XP_005264262.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.65 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. |
Molecular Function |
Calcium |
Subcellular Location |
Secreted; Extracellular space |
Expression |
In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina. |
Structure |
Interacts with ECM1. Interacts with TIMP3. |
Alternative Nomenclature |
DHRD antibody Doyne honeycomb retinal degeneration antibody DRAD antibody EFEMP 1 antibody Epidermal growth factor containing fibulin like extracellular matrix protein 1 antibody FBLN3 antibody Fibrillin like antibody FIBULIN 3 antibody FLJ35535 antibody Heat shock 70 KD protein 1 antibody MGC111353 antibody MLVT antibody T16 protein antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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EFP-101AP | |||
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P-EFP | |||
|
EFP-BIOTIN | |||
|
PC-EFP | |||
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