Phospho-PARP1 Positive Control

General Information

Product

Phospho-PARP1 Positive Control

Description

Western Blot Positive Control Phospho-specific Poly ADP-ribose polymerase 1

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_001609

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

P09874

Overview

Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine, histidine or tyrosine ADP-ribosylation of proteins.

Molecular Function

Allosteric enzyme, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase

Expression

Expressed in ventricular zone and 212 other cell types or tissues.

Structure

Homodimer; PARP-type zinc-fingers from separate PARP1 molecules form a dimer module that specifically recognizes DNA strand breaks.

Alternative Nomenclature

ADP-ribosyltransferase diphtheria toxin-like 1

DNA ADP-ribosyltransferase PARP1

Protein poly-ADP-ribosyltransferase PARP1

PARP1

ADPRT

PPOL