BST2 Antibody

Product no.: BST2-201AP

General Information
Product	BST2 Antibody
Description	Affinity Purified Bonemarrow stromal antigen 2 Antibody N-epitope
Verified Applications	ELISA, CM, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human
Immunogen	N-epitope Synthetic peptide taken within amino acid region 1-50 on human Bonemarrow stromal antigen 2 protein.
Accession #	GenBank: BAD96844
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.62 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:2,000
ELISA	1:2,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Immunoprecipitation	1:200
Western Blot	1:500-1:1,000
Protein
Uniprot #	Q10589
Overview	IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.
Molecular Function	Antiviral defense; B-cell activation; Immunity; Innate immunity
Subcellular Location	Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane
Expression	Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.
Structure	Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.
Alternative Nomenclature	Bone marrow stromal antigen 2 antibody Bone marrow stromal cell antigen 2 antibody BST 2 antibody CD 317 antibody CD317 antigen antibody HM1.24 antigen antibody NPC A 7 antibody Tetherin antibody

Protein information supplied by UniProt

Fabgennix BST2 Antibody has been used in 3 Publications

Sayeed, Aejaz et al. “Aberrant Regulation of the BST2 (Tetherin) Promoter Enhances Cell Proliferation and Apoptosis Evasion in High Grade Breast Cancer Cells.” Ed. Aamir Ahmad. PLoS ONE 8.6 (2013): e67191. PMC3688682

Immunocytochemistry, Immunohistochemistry, Western Blot; Human

Cao, Wei et al. “Regulation of TLR7/9 Responses in Plasmacytoid Dendritic Cells by BST2 and ILT7 Receptor Interaction.” The Journal of Experimental Medicine 206.7 (2009): 1603–1614. PMC2715090

Western Blot; Human

Cai, Dongqing et al. “Up-Regulation of Bone Marrow Stromal Protein 2 (BST2) in Breast Cancer with Bone Metastasis.” BMC Cancer 9 (2009): 102. PMC2674058

Immunohistochemistry, Western Blot; Human

Publishing research using BST2-201AP? Please let us know, we can cite the reference in this datasheet.

Customer ratings for BST2 Antibody

Number of ratings: 1
Average rating: 5

5 stars
from Anonymous on 12/20/2019

All incoming ratings are posted by actual shop visitors / webshop customers and their content is checked by the operator by means of a visual inspection.