General Information |
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Product |
TYRO3 Positive Control |
Description |
Western Blot Positive Control Tyrosine-protein kinase receptor TYRO3 |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
NCBI: NP_006284.2 |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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|
Western Blot |
1:500-1:750 |
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Uniprot # |
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Overview |
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. |
Molecular Function |
Kinase, Receptor, Transferase, Tyrosine-protein kinase |
Subcellular Location |
Cell membrane; Single-pass Type I membrane protein |
Expression |
Abundant in the brain and lower levels in other tissues. |
Structure |
Monomer and homodimer. Interacts (via N-terminus) with extracellular ligands TULP1 and GAS6. Interacts with PIK3R1; this interaction increases PI3-kinase activity. |
Alternative Nomenclature |
Brt BYK DTK RSE SKY Tif TYRO3 Tyrosine-protein kinase byk Tyrosine-protein kinase DTK Tyrosine-protein kinase receptor TYRO3 Tyrosine-protein kinase RSE Tyrosine-protein kinase SKY |
Protein information supplied by UniProt
Fabgennix TYRO3 Antibody has been used in 1 Publication |
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Uehara, Hiroshi, and Emily Shacter. "Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells." The Journal of Immunology 180.4 (2008): 2522-2530. PMID18250462
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Western Blot; Human |
Publishing research using TYRO3-101AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
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TYRO3-101AP | |||
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TYRO3-FITC | |||
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P-TYRO3 | |||
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TYRO3-BIOTIN | |||
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