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General Information
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Product
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alpha Synuclein Peptide
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Description
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Antigenic Blocking Peptide alpha-synuclein isoform NACP112
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Verified Applications
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Immunocompetition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 62-112 unique sequence on alpha-synuclein isoform NACP 112 protein.
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Accession #
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NCBI: NP_009292
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P37840
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Overview
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May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
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Molecular Function
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Alpha-tubulin binding, Calcium-ion binding, copper ion binding
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Subcellular Location
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cytoplasm, Membrane, Nucleus, Cell junction > synapse
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Expression
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Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
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Structure
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Soluble monomer which can form filamentous aggregates. Interacts with UCHL1. Interacts with phospholipase D and histones.
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Alternative Nomenclature
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Alpha synuclein antibody
MGC105443 antibody
MGC110988 antibody
MGC127560 antibody
NACP antibody
PARK 1 antibody
PARK 4 antibody
PD 1 antibody
SNCA antibody
SYN antibody
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Alpha Synuclein Antibody
Alpha Synuclein Antibody FITC
Alpha Synuclein Antibody BIOTIN
Alpha Synuclein Positive Control
