General Information |
|
Product |
C6orf150 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Cyclic GMP-AMP synthase Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 450-500 on mouse cGAS protein. |
Accession # |
NCBI: NP_775562 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.60 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Catalyzes the formation of cyclic GMP-AMP from ATP and GTP. Has antiviral activity through acting as a cystolic DNA senser. |
Molecular Function |
Nucleotidyltransferase; ATP binding; DNA binding |
Subcellular Location |
Cytoplasm; Cytosol |
Expression |
Is expressed in the monocytic cell line THP1 by type 1 Interferons |
Structure |
Monomer when in absence of DNA. Homodimer when bound to DNA. |
Alternative Nomenclature |
C6orf150 antibody cGAMP synthase antibody cGAS antibody Chromosome 6 open reading frame 150 antibody Cyclic GMP-AMP synthase antibody h-cGAS antibody Hypothetical protein LOC115004 antibody Mab 21 domain containing 1 antibody MB21D1 antibody protein MB21D1 antibody Uncharacterized protein C6orf150 antibody |
Protein information supplied by UniProt
Fabgennix cGAS Antibody has been used in 1 Publication |
|
Iijima, Kenta, Shigeyuki Kano, and Yukihito Ishizaka. “Viral protein R of human immunodeficiency virus type‐1 induces retrotransposition and upregulates glutamate synthesis by the signal transducer and activator of transcription 1 signaling pathway.“ Microbiology and Immunology (2015).PMID25990091 |
Western Blot; Mouse |
Publishing research using CGAS-101AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
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P-CGAS.1 | |||
|
CGAS-101AP | |||
|
CGAS101-FITC | |||
|
PC-CGAS | |||
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