General Information
Product
DCC Antibody
Description
Affinity Purified Netrin Receptor DCC Antibody
Verified Applications
ELISA, IP, WB
Host
Rabbit
Species Cross Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide taken within amino acid region 1330-1380 on rat DCC protein.
Physical Properties
Quantity
100 µg
Volume
200 µl
Concentration
0.5-.70 µg/µl in antibody stabilization buffer
Form
Affinity Purified
Clonality
Polyclonal
Storage
-20°C for long term storage
Application Protocol
DB
1:10,000
ELISA
Western Blot
1:500
Protein
Uniprot #
P43146
Overview
Receptor for netrin required for axon guidance; may trigger signaling for axon repulsion; acts as a dependence receptor required for apoptosis induction; tumor suppressor gene.
Molecular Function
netrin receptor activity; transcription coactivator activity; transmembrane signaling receptor activity; Developmental protein
Subcellular Location
axon; cytosol; plasma membrane
Expression
Found in axons of the central and peripheral nervous system; differentiated cell types of the intestine
Structure
Belongs to the immunoglobulin superfamily. DCC family; Contains 6 fibronectin type-III domains; Contains 4 Ig-like C2-type (immunoglobulin-like) domains
Alternative Nomenclature
Colorectal cancer related chromosome sequence 18 antibody
CRC 18 antibody
CRCR 1 antibody
DCC antibody
Deleted in colorectal cancer protein antibody
Immunoglobulin superfamily DCC subclass member 1 antibody
Netrin receptor DCC antibody
Tumor suppressor protein DCC antibody
Protein information supplied by UniProt
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