General Information
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Product
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POMT1 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Protein O-mannosyl-transferase 1 isoform a Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 400-460 on human POMT1 protein.
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Accession #
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NCBI: NP_009102.3
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DOT Blot
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry
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1:50
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9Y6A1
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Overview
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Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient.
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Molecular Function
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mannosyltransferase activity, metal ion binding
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Subcellular Location
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Endoplasmic reticulum membrane, multi-pass membrane protein
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Expression
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Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver.
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Alternative Nomenclature
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Dolichyl phosphate mannose protein mannosyltransferase 1 antibody
LGMD2K antibody
POMT 1 antibody
Protein O mannosyl transferase 1 antibody
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