General Information
|
|
Product
|
PAX5 Antibody
|
Description
|
Affinity Purified Paired box protein PAX-5 Antibody N-epitope
|
Verified Applications
|
ELISA, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human
|
Immunogen
|
Synthetic peptide taken within amino acid region 1-50 on human PAX5 protein.
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.65-0.75 µg/µl in antibody stabilization buffer
|
Form
|
Affinity Purified
|
Clonality
|
Polyclonal
|
Determinant
|
N-epitope
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
Q02548
|
Overview
|
May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
|
Molecular Function
|
Developmental protein, RNA polymerase II core promoter proximal region sequence-specific DNA binding
|
Subcellular Location
|
Nucleus
|
Expression
|
Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
|
Structure
|
Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4. Interacts with ETS1, altering its DNA-binding properties.
|
Alternative Nomenclature
|
- B cell lineage specific activator antibody
- BSAP antibody
- EBB-1 antibody
- KLP antibody
- Paired box 5 antibody
- PAX 5 antibody
- Transcription factor PAX 5 antibody
|
|
|