General Information

Product

XTP4 Antibody

Description

Affinity Purified Chromosome17 orf 37 Antibody Mid-Region

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 20-70 on human XTP4 protein.

Accession #

GenBank: AF490253.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.83 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:2,000

ELISA

1:2,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q9BRT3

Overview

Increases cell migration by induction of filopodia formation at leading edge.  Regulates apoptosis and redox-related process.

Molecular Function

Apoptosis

Subcellular Location

Cytoplasm; Cytosol; Cell membrane; Lipid anchor

Expression

Present in Leydig cells.  Up-regulated in breast cancers and brain cancer distant metastasis also up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma.

Structure

Belongs to SelWTH family

Alternative Nomenclature

C17orf37 antibody

C17orf37 homolog antibody

C35 antibody

chromosome 17 open reading frame 37 antibody

HBV X transactivated gene 4 protein antibody

HBV XAg transactivated protein 4 antibody

MGC14832 antibody

Mien1 antibody

Migration and invasion enhancer 1 antibody

ORB3 antibody

Protein C17orf37 antibody

Protein C35 antibody

RDX12 antibody

Redox protein, 12-KD antibody

XTP4 antibody

General Information

Product

XTP4 Antibody

Description

Affinity Purified Chromosome17 orf 37 Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 40-90 on human XTP4 protein.

Accession #

GenBank: AF490253.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.83 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:2,000

ELISA

1:2,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q9BRT3

Overview

Increases cell migration by induction of filopodia formation at leading edge.  Regulates apoptosis and redox-related process.

Molecular Function

Apoptosis

Subcellular Location

Cytoplasm; Cytosol; Cell membrane; Lipid anchor

Expression

Present in Leydig cells.  Up-regulated in breast cancers and brain cancer distant metastasis also up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma.

Structure

Belongs to SelWTH family

Alternative Nomenclature

C17orf37 antibody

C17orf37 homolog antibody

C35 antibody

chromosome 17 open reading frame 37 antibody

HBV X transactivated gene 4 protein antibody

HBV XAg transactivated protein 4 antibody

MGC14832 antibody

Mien1 antibody

Migration and invasion enhancer 1 antibody

ORB3 antibody

Protein C17orf37 antibody

Protein C35 antibody

RDX12 antibody

Redox protein, 12-KD antibody

XTP4 antibody

General Information

Product

HE4 Antibody Affinity Purified

Description

Affinity Purified WAP domain containing protein HE4-V2/V3 Antibody N-epitope

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human WAP four-disulfide core domain protein 2.

Accession #

NCBI:  NP_006094.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Immunoprecipitation

1:200

Western Blot

1:500-1:750

Protein

Uniprot #

Q14508

Overview

Broad range protease inhibitor

Molecular Function

Aspartic protease inhibitor, Protease inhibitor, Serine protease inhibitor, Thiol protease inhibitor

Subcellular Location

extracellular space; extracellular vesicular exosome; Secreted

Expression

male reproductive system;regions of the respiratory tract;nasopharynx;number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines.Initially described as being exclusively transcribed in the epididymis

Structure

Homotrimer; disulfide-linked

Alternative Nomenclature

EDDM4 antibody

epididymal protein 4 antibody

Epididymal secretory protein E4 antibody

Epididymis specific whey acidic protein type four disulfide core antibody

HE 4 antibody

Major epididymis specific protein E4 antibody

Putative protease inhibitor WAP5 antibody

WAP domain containing protein HE4 antibody

WAP four disulfide core domain 2 antibody

WAP5 antibody

WFDC2 antibody

General Information

Product

IL23 P19 Antibody

Description

Affinity Purified Interleukin-23 subunit alpha Antibody C-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to C terminal region amino acids 162-179 of Human IL23 P19. Peptide was covalently modified.

Sequence:

FKILRSLQAFAAVAARV

Accession #

NCBI:  NP_057668.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:250

Protein

Uniprot #

Q9NPF7

Overview

a heterodimeric cytokine which functions in innate and adaptive immunity;stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines;IL-23 induces autoimmune inflammation

Molecular Function

Cytokine

Subcellular Location

Secreted

Expression

Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level)

Structure

Heterodimer

Alternative Nomenclature

alpha subunit P19 antibody

IL-23 subunit alpha antibody

IL-23-A antibody

IL-23p19 antibody

IL23 antibody

interleukin 23 alpha subunit p19 antibody

JKA3 induced upon T cell activation antibody

MGC79388 antibody

P19 antibody

SGRF antibody

General Information

Product

IL23 P19 Antibody

Description

Affinity Purified Interleukin-23 subunit alpha Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 75-105 on IL23P19 protein.

Accession #

NCBI:  NP_057668.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:250

Protein

Uniprot #

Q9NPF7

Overview

a heterodimeric cytokine which functions in innate and adaptive immunity;stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines;IL-23 induces autoimmune inflammation

Molecular Function

Cytokine

Subcellular Location

Secreted

Expression

Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level)

Structure

Heterodimer

Alternative Nomenclature

alpha subunit P19 antibody

IL-23 subunit alpha antibody

IL-23-A antibody

IL-23p19 antibody

IL23 antibody

interleukin 23 alpha subunit p19 antibody

JKA3 induced upon T cell activation antibody

MGC79388 antibody

P19 antibody

SGRF antibody

General Information

Product

NAPSIN A Antibody

Description

Affinity Purified Napsin A aspartic peptidase Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human Napsin A protein.

Accession #

GenBank: EAW71848.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.85-1.25 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O96009

Overview

May be involved in processing of pneumocyte surfactant precursors

Molecular Function

aspartic-type endopeptidase activity; peptidase activity

Subcellular Location

alveolar lamellar body; extracellular space; extracellular vesicular exosome; lysosome

Expression

Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.

Structure

Belongs to the peptidase A1 family.

Alternative Nomenclature

ASP 4 antibody Aspartyl protease 4 antibody
KAP antibody
Kdap antibody
Kidney derived aspartic protease like protein antibody
NAP1 antibody
NAPA antibody
NAPSA antibody

Napsin 1 antibody
napsin A aspartic peptidase antibody Pronapsin A antibody
SNAPA antibody
TA01/TA02 antibody

General Information

Product

NAPSIN A Antibody

Description

Affinity Purified Napsin A aspartic peptidase Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on human Napsin A protein.

Accession #

GenBank: EAW71848.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.85-1.25 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O96009

Overview

May be involved in processing of pneumocyte surfactant precursors

Molecular Function

aspartic-type endopeptidase activity; peptidase activity

Subcellular Location

alveolar lamellar body; extracellular space; extracellular vesicular exosome; lysosome

Expression

Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.

Structure

Belongs to the peptidase A1 family.

Alternative Nomenclature

ASP 4 antibody Aspartyl protease 4 antibody
KAP antibody
Kdap antibody
Kidney derived aspartic protease like protein antibody
NAP1 antibody
NAPA antibody
NAPSA antibody

Napsin 1 antibody
napsin A aspartic peptidase antibody Pronapsin A antibody
SNAPA antibody
TA01/TA02 antibody

General Information

Product

LYK5 Antibody

Description

Affinity Purified STE20-related kinase adapter protein alpha Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 381-431 on human STE-20 related kinase adapter protein alpha.

Accession #

NCBI:  NP_001003787.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q7RTN6

Overview

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Molecular Function

ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups

Subcellular Location

Nucleus, cytoplasm

Expression

Expressed in liver

Structure

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Contains 1 protein kinase domain.

Alternative Nomenclature

Protein kinase LYK5 antibody

Serologically defined breast cancer antigen NY BR 96 antibody

STE20 related adapter protein antibody

STRAD alpha antibody

STRAD antibody

General Information

Product

LYK5 Antibody

Description

Affinity Purified STE20-related kinase adapter protein alpha Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human STE-20 related kinase adapter protein alpha.

Accession #

NCBI:  NP_001003787.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q7RTN6

Overview

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Molecular Function

ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups

Subcellular Location

Nucleus, cytoplasm

Expression

Expressed in liver

Structure

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Contains 1 protein kinase domain.

Alternative Nomenclature

Protein kinase LYK5 antibody

Serologically defined breast cancer antigen NY BR 96 antibody

STE20 related adapter protein antibody

STRAD alpha antibody

STRAD antibody

General Information

Product

EpCAM Antibody

Description

Affinity Purified Tumor-associated Calcium signal transducer 1 Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 215-265 on human Tumor-associated calcium signal transducer 1 protein.

Accession #

GenBank: EAX00219.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.78 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

UPI0000EE24A7

Overview

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

Molecular Function

Tumor antigen

Subcellular Location

Cell junction, Cell membrane, Membrane, Tight junction

Expression

Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.

Structure

Belongs to EPCAM family.  Contains 1 thryoglobulin type-1 domain.

Alternative Nomenclature

17 1A antibody

323/A3 antibody

Adenocarcinoma associated antigen antibody

Antigen identified by monoclonal antibody AUA1 antibody

CD326 antibody

Cell surface glycoprotein Trop 1 antibody

Cell surface glycoprotein Trop 2 antibody

CO17 1A antibody

DIAR5 antibody

EGP antibody

EGP2 antibody

EGP314 antibody

EGP40 antibody

Ep CAM antibody

Epithelial cell adhesion molecule antibody

Epithelial glycoprotein 314 antibody

ESA antibody

GA733 1 antibody

gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody

HNPCC8 antibody

Human epithelial glycoprotein 2 antibody

KS 1/4 antigen antibody

KSA antibody

Lymphocyte antigen 74 antibody

M1S 1 antibody

M1S2 antibody

M4S1 antibody

Major gastrointestinal tumor associated protein GA733 2 antibody

Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody

MIC18 antibody

MK 1 antibody

TACD1 antibody

TROP1 antibody

Tumor associated calcium signal transducer 1 antibody

Tumor associated calcium signal transducer 2 precursor antibody