General Information |
|
Product |
Nogo Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Reticulon-4 isoform A Antibody |
Verified Applications |
ELISA, IHC, IP ,WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 1100-1200 on Nogo AS protein. |
Accession # |
NCBI: NP_065393.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.59-0.63 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. |
Molecular Function |
poly(A) RNA binding |
Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein |
Expression |
Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 is widely expressed except for the liver. Isoform 3 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 is testis-specific. |
Structure |
Binds to RTN4R, interacts with Bcl-xl and Bcl-2. Isoform 2 binds to NGBR and RTN3. Isoform 2 and Isoform 3 interact with BACE1 and BACE2, interacts with RTN4IP1 and ATL1. |
Alternative Nomenclature |
1110020G17Rik antibody AA407876 antibody AA409940 antibody AA960376 antibody ASY antibody C130026I10Rik antibody Foocen antibody Glut4 vesicle 20 kDa protein antibody Human NogoA antibody Kiaa0886 antibody KIAA4153 antibody MGC116054 antibody MGC139261 antibody mKIAA0886 antibody mKIAA4153 antibody My043 protein antibody Nbla00271 antibody Nbla10545 antibody Neurite growth inhibitor 220 antibody Neuroendocrine-specific protein antibody NI-250 antibody Nogo A antibody NOGO antibody Nogo B antibody Nogo C antibody NSP antibody NSP CL antibody rat N antibody Reticulon 4 antibody Reticulon 5 antibody RTN X antibody RTN4 A antibody RTN4-B1 antibody Vp20 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-NOGO | |||
|
NOGO-101AP | |||
|
NOGO-FITC | |||
|
PC-NOGO | |||
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