General Information
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Product
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Septin 2 Antibody FITC
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Description
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FITC-Conjugated Septin 2 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 270-320 on human Septin-2 protein.
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Accession #
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Gen Bank: AAH14455.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q15019
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Overview
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Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating effiecient vesicle transport, and by impeding MAP4 binding to tubulin. Required for progression through mitosis.
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Molecular Function
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Enzyme regulator activity
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Subcellular Location
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Cytoplasm, cytoskeleton, spindle, cleavage furrow, midbody, cell cortex, cilium membrane
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Expression
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Widely expressed. Up-regulated in liver cancer.
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Alternative Nomenclature
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DIFF6 antibody
KIAA0158 antibody
NEDD 5 antibody
Neural precursor cell expressed developmentally down regulated protein 5 antibody
Pnutl3 antibody
Protein NEDD5 antibody
septin 2 antibody
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