General Information
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Product
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PGCF Antibody FITC-Conjugated
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Description
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FITC-Conjugated Guanylyl Cyclase F Antibody
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Verified Applications
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CM, ELISA, ICC, IF, IHC, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein.
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Accession #
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GenBank: L36029.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.75-1.20 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:200
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:200
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Immunofluorescence
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1:200
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Immunohistochemistry
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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P51842
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Overview
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Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
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Molecular Function
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Lyase
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Subcellular Location
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Membrane; Single-pass type I membrane protein
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Expression
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Expressed only in the eye.
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Structure
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Belongs to the adenylyl cyclase-class-4/guanylyl cyclase family. Contains 1 guanylate cyclase domain. Contains 1 protein kinase domain.
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Alternative Nomenclature
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Particulate Guanylate Cyclase F antibody
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