General Information
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Product
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GFAP Antibody
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Description
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Affinity Purified Glial fibrillary acidic protein Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 50-100 on human glial fibrillary acidic protein.
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Accession #
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PRF: 226236
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:100 |
Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P14136
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Overview
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GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
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Molecular Function
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Structural Constituent of Cytoskeleton; Astrocyte development; Bergmann glial cell differentiation
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Subcellular Location
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Cytoplasm
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Expression
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Expressed in cells lacking fibronectin.
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Structure
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Interacts with SYNM (By similarity). Isoform 3 interacts with PSEN1 (via N-terminus).
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Alternative Nomenclature
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Astrocyte antibody
FLJ42474 antibody
FLJ45472 antibody
GFAP antibody
Glial Fibrillary Acidic Protein antibody
Intermediate filament protein antibody
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