General Information |
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Product |
EGR2 Positive Control |
Description |
Western Blot Positive Control E3 SUMO-protein ligase EGR2 / KROX20 Antibody |
Verified Applications |
WB |
Immunogen |
Purified Protein |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:2,500-1:5,000 |
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Uniprot # |
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Overview |
Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. |
Molecular Function |
chromatin binding DNA binding HMG box domain binding ligase activity metal ion binding RNA polymerase II activating transcription factor binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activ |
Subcellular Location |
Nucleus |
Expression |
Expressed in mammary tumors (at protein level). Expressed mainly in adult thymus and embryonic nervous system. |
Structure |
Belongs to the EGR C2H2-type zinc-finger protein family. |
Alternative Nomenclature |
AT591 antibody CMT1D antibody CMT4E antibody E3 SUMO-protein ligase EGR2 antibody Early growth response 2 antibody EGR-2 antibody FLJ14547 antibody KROX 20 Drosophila homolog antibody KROX20 antibody Zinc finger protein Krox-20 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
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KROX20-101AP | |||
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KROX20-BIOTIN | |||
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KROX20-FITC | |||
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P-KROX20 | |||
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