General Information |
|
Product |
ETS1 associated protein II Antibody FITC |
Description |
FITC-Conjugated tyrosyl-DNA phosphodiesterase 2 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 330-360 on human Tyrosyl-DNA phosphodiesterase protein. |
Accession # |
NCBI: NP_057698.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.58 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation | 1:200 |
Western Blot |
1:1,000 |
|
|
Uniprot # |
|
Overview |
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. |
Molecular Function |
5'-tyrosyl-DNA phosphodieseterase activity, magnesium ion binding, manganese ion binding, nuclease activity, transcription corepressor activity, single-stranded DNA binding. |
Subcellular Location |
nucleus, PML body, cytoplasm |
Expression |
Widely expressed |
Alternative Nomenclature |
5'-tyrosyl-DNA phosphodiesterase antibody AD 022 antibody dJ30M3.3 antibody EAP 2 antibody ETS 1 associated protein 2 antibody RP1-30M3.3 antibody TRAF and TNF receptor associated protein antibody TTRAP antibody Tyr DNA phosphodiesterase 2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TDP2-201AP | |||
|
P-TDP2 | |||
|
TDP2-BIOTIN | |||
|
PC-TDP2 | |||
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