General Information
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Product
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LILRB3 Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 800-841 on mouse LILRB3 protein.
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Accession #
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NCBI: NP_035225.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.74 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:20,000
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ELISA
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1:20,000
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Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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P97484
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Overview
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May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
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Subcellular Location
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Cell membrane, single-pass type I membrane protein
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Expression
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Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells.
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Alternative Nomenclature
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CD85 antigen like family member A antibody
HL9 antibody
IL T5 antibody
Immunoglobulin like transcript 5 antibody
LIR 3 antibody
Monocyte inhibitory receptor HL9 antibody
PIRB antibody
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