General Information |
|
Product |
PDE2A1 Peptide |
Description |
Antigenic Blocking Peptide Phosphodiesterase 2A1 |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide corresponding to region within amino acids 1-50 on N-terminus of human PDE2A1 protein. |
Accession # |
NCBI: NP_001230713.1 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration. |
Molecular Function |
Calcium channel activity, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; drug binding; metal ion binding; protein homodimerization activity; TPR domain binding |
Subcellular Location |
Cytoplasm |
Expression |
Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas. |
Structure |
Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily. Contains 2 GAF domains. |
Alternative Nomenclature |
Phosphodiesterase 2A 1 |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
PC-PD2A1 | |||
|
PD2A1-101AP | |||
|
PD2A1-BIOTIN | |||
|
PD2A1-FITC | |||
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