General Information |
|
Product |
TdT Peptide |
Description |
Antigenic Blocking Peptide DNA nucleotidylexotransferase Extreme C-epitope |
Verified Applications |
Immunocompeition, Immunodepletion |
Peptide Description |
Synthetic peptide taken within amino acid region 459-509 on human Terminal deoxynucleotidyltransferase protein. |
Accession # |
NCBI: NP_004079 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Determinant |
Extreme C-epitope |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
Molecular Function |
Nucleotidyltransferase, Transferase, DNA binding |
Subcellular Location |
Nucleus |
Structure |
Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone. Released from this complex by PCNA. |
Alternative Nomenclature |
Deoxynucleotidyltransferase terminal antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TDT-112AP | |||
|
TDT.112-FITC | |||
|
TDT.112-BIOTIN | |||
|
PC-TDT | |||
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