General Information
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Product
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TLR1 Peptide
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Description
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Antigenic Blocking Peptide Toll-like receptor 1
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Verified Applications
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Immunocompeition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 370-420 on human Toll-like receptor 1.
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Accession #
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GenBank: AAI09094.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q15399
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Overview
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Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
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Molecular Function
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Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding
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Subcellular Location
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Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein
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Structure
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Binds MYD88 (via TIR domains). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2. Interacts with CNPY3.
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Alternative Nomenclature
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CD281 antibody
CD281 antigen antibody
KIAA0012 antibody
LPRS5 antibody
rsc786 antibody
Similar to Drosophila Toll protein antibody
TIL antibody
TIL. LPRS5 antibody
Tlr1 antibody
Toll (Drosophila) homolog antibody
Toll like receptor 1 antibody
Toll like receptor 1 Precursor antibody
Toll/Interleukin 1 receptor like antibody
Toll/interleukin-1 receptor-like protein antibody
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