General Information |
|
Product |
EAAT1 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Excitatory Amino Acid Transporter 1 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to C terminal amino acids 480-543 of Mouse EAAT1 protein. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using heterobifunctional cross linker for immunogen preparation.
Sequence: KPYQLIAQDNEPEKPVADSETK |
Specificity | Will not cross react with EAAT2 protein. |
Accession # |
NCBI: NP_683740.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.61 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. |
Molecular Function |
high-affinity glutamate transmembrane transporter activity;sodium:dicarboxylate symporter activity |
Subcellular Location |
plasma membrane; cell surface; fibril;neuronal cell body |
Expression |
Purkinje cell layer in cerebellum,lung,spleen, skeletal muscle and testis. |
Structure |
Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A3 subfamily has a Transmembrane helix. |
Alternative Nomenclature |
EA6 antibody EAAT1 antibody Excitatory amino acid transporter 1 antibody FLJ25094 antibody GLAST antibody Glial high affinity glutamate transporter antibody glutamate/aspartate transporter, high affinity, sodium-dependent antibody High affinity neuronal glutamate transporter antibody Slc1a3 antibody Sodium dependent glutamate/aspartate transporter antibody Solute carrier family 1 member 3 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
EAAT1-101AP | |||
|
P-EAAT1 | |||
|
EAAT1-BIOTIN | |||
|
PC-EAAT1 | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.