General Information |
|
Product |
BTK Peptide |
Description |
Antigenic Blocking Peptide Bruton's Tyrosine Kinase Antibody |
Verified Applications |
Immmunodepletion, Competition Assay |
Peptide Description |
Synthetic peptide taken within amino acid region 550-650 on human BTK protein. |
Accession # |
NCBI: NP_000052.1 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Non-receptor tyrosine kinase invovled in B lymphocyte development. |
Molecular Function |
Kinase; Transferase; Tyrosine-protein Kinase |
Subcellular Location |
Cytoplasm; Cell Membrane; Peripheral membrane: Nucleus. In steady state BTK is predominantly cytosolic. |
Expression |
B-lymphocytes |
Structure |
PH domain mediates binding to inositol polyphosphate and phosphoinositides, leading to its targeting with plasma membrane. Extended in the BTK kinase family by a region designated Tec homology domain, which has roughly 80 residues preceding SH3 domain. |
Alternative Nomenclature |
Agammaglobulinaemia tyrosine kinase antibody AGMX 1 antibody AT antibody ATK antibody B cell progenitor kinase antibody BPK antibody Bruton tyrosine kinase antibody Btk antibody IMD1 antibody PSCTK 1 antibody Tyrosine protein kinase BTK antibody XLA antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
BTK-101AP | |||
|
BTK-FITC | |||
|
BTK-BIOTIN | |||
|
PC-BTK | |||
Display accessory details |
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