General Information |
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Product |
Particulate Guanylate Cyclase C Positive Control |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
GenBank: AAA41201.1 |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin. |
Molecular Function |
Lyase, Receptor |
Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane |
Structure |
Homotrimer. Interacts via its C-terminal region with PDZK2. Interacts with the lectin chaperone VIP36 |
Alternative Nomenclature |
ANP C antibody ANPRC antibody Atrial natriuretic peptide C type receptor antibody Atrionatriuretic peptide receptor C antibody C5orf23 antibody FLJ14054 antibody GUCY2B antibody MGC22189 antibody Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) antibody NPR 3 antibody NPR C antibody Guanylyl Cyclase C antibody NPR-C antibody |
Protein information supplied by UniProt
Fabgennix PGCC Antibody has been used in 3 Publications |
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Han, Xiaonan et al. “Loss of Guanylyl Cyclase C (GCC) Signaling Leads to Dysfunctional Intestinal Barrier.” Ed. Guillaume Dalmasso. PLoS ONE 6.1 (2011): e16139. PMC3031533
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Confocal Microscopy; Immunofluorescence; Immunohistochemistry; Western Blot; Mouse |
Garin-Laflam, M. P. et al. “Activation of Guanylate Cyclase C Signaling Pathway Protects Intestinal Epithelial Cells from Acute Radiation-Induced Apoptosis.” American Journal of Physiology - Gastrointestinal and Liver Physiology 296.4 (2009): G740–G749. PMC2670662
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Western Blot; Mouse |
Liu, Cambrian Y., Scott E. Fraser, and David S. Koos. "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." Journal of Comparative Neurology 516.1 (2009): 36-48. PMID19565523
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Immunofluorescence, Western Blot; Mouse |
Publishing research using PGCC-301AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
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PGCC-301AP | |||
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PGCC-FITC | |||
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P-PGCC | |||
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PGCC-BIOTIN | |||
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