General Information |
|
Product |
Protein Vestigial Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Vestigial Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Drosophila melanogaster |
Immunogen |
Synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Vestigial protein. |
Accession # |
NCBI: NP_523723.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.65-0.75 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Involved in determining which thoracic imaginal disk cells will form wings and halteres, perhaps by interacting with other nuclear regulatory proteins. When in combination with scalloped (sd), it acts as a transcriptional activation complex that regulates gene expression in the wing. Binding to sd switches the DNA target selectivity of sd. Required and sufficient for cell proliferation at the dorsal/ventral (D/V) boundary of the wing imaginal disk. Also required for cell proliferation in the wing imaginal disk, mediated via activation of E2f. By interacting with Dhfr, may control genes involved in DNA replication. |
Molecular Function |
DNA binding; Protein C-terminus binding |
Subcellular Location |
Nucleus |
Expression |
Expressed in the developing wing primordia initially along the D/V wing boundary, and by the late third larval instar, maximal expression is seen in cells at the D/V wing disk boundary. Less expression is seen in cells located farther from this boundary. |
Alternative Nomenclature |
VG VSTGL VG21 DMEL/CG3830 CCG3830 |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-PVSTGL | |||
|
PVSTGL-140AP | |||
|
PVSTGL-FITC | |||
|
PC-PVSTGL | |||
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