General Information
|
|
Product
|
5HT2C Receptor Antibody BIOTIN
|
Description
|
BIOTIN-Conjugated 5-hydroxytryptamine receptor 2C Antibody
|
Verified Applications
|
ELISA, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 400-458 on human 5-hydroxytryptamine receptor 2C.
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.5 µg/µl in antibody stabilization buffer
|
Immunoglobulin
|
IgG
|
Form
|
BIOTIN-Conjugated
|
Purification Method
|
Immobilized antigen affinity chromatography
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
ELISA
|
1:50,000
|
Immunocytochemistry
|
1:50-1:100
|
Immunohistochemistry
|
1:50-1:100
|
Immunoprecipitation
|
1:200
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P28335
|
Overview
|
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.
|
Molecular Function
|
G-protein coupled receptor, Receptor, Transducer
|
Subcellular Location
|
Cell membrane, Multi-pass membrane protein
|
Expression
|
Detected in brain.
|
Structure
|
The PDZ domain-binding motif is involved in the interaction with PATJ, CASK, APBA1, DLG1 and DLG4.
|
Alternative Nomenclature
|
5 Hydroxytryptamine 2C receptor antibody
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody
5-hydroxytryptamine receptor 1C antibody
5-hydroxytryptamine receptor 2C antibody
5HT1C antibody
5HT2C antibody
5HTR2C antibody
5Hydroxytryptamine 2C receptor antibody
Htr1c antibody
HTR2C antibody
serotonin 1c receptor antibody
serotonin 2c receptor antibody
Serotonin receptor 2C antibody
|
|
|