General Information |
|
Product |
TdT Antibody FITC |
Description |
FITC-Conjugated DNA nucleotidylexotransferase isoform 2 Antibody C-epitope |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Chicken, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 450-500 on human Terminal deoxynucleotidyltransferase protein. |
Accession # |
NCBI: NP_004079 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.6 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:250 |
Dot Blot |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:250 |
Immunofluorescence |
1:250 |
Immunohistochemistry |
1:250 |
Immunoprecipitation |
1:250 |
Western Blot |
1:1,000 |
|
|
Uniprot # |
|
Overview |
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
Molecular Function |
Nucleotidyltransferase, Transferase, DNA binding |
Subcellular Location |
Nucleus |
Structure |
Interacts with PRP19 and DNTTIP1. Forms a ternary complex with DNTTIP2 and core histone. Released from this complex by PCNA. |
Alternative Nomenclature |
Deoxynucleotidyltransferase terminal antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TDT-101AP | |||
|
P-TDT.101 | |||
|
TDT.101-BIOTIN | |||
|
PC-TDT | |||
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