General Information

Product

GGCX Antibody 

Description

Affinity Purified Gamma-glutamic carboxylase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-450 on human GGCX protein.

Accession #

GenBank: AAA91834.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P38435

Overview

Mediates the vitamin K-dependent carboxylation of glutatmate residues to calcium-binding gamma-carboxyglutamate residues with the concomitant converstion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.

Molecular Function

gamma-glutamyl carboxylase activity; Lyase

Subcellular Location

Endoplasmic Reticulum membrane; Multi-pass membrane protein

Expression

Monomer; may interact with CALU

Alternative Nomenclature

FLJ26629 antibody

Gamma glutamyl carboxylase antibody

Gamma-glutamyl carboxylase antibody

GC antibody

GGCX antibody

Peptidyl glutamate 4 carboxylase antibody

Peptidyl-glutamate 4-carboxylase antibody

Vitamin K dependent gamma carboxylase antibody

Vitamin K gamma glutamyl carboxylase antibody

Vitamin K-dependent gamma-carboxylase antibody

VKCFD 1 antibody

VKCFD1 antibody

VKGC_HUMAN antibody

General Information

Product

Annexin A9 Antibody

Description

Affinity Purified annexin A9 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-100 on human Annexin A9 protein.

Accession #

NCBI:  NP_003559

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O76027

Overview

Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.

Molecular Function

acetylcholine receptor activity; phospholipid binding; synaptic transmission; calcium ion binding

Subcellular Location

Cell surface; cytosol; extracellular vesicular exosome

Expression

Expressed in the stratified squamous skin epithelium, but not in epithelia of other types.

Structure

Homodimer

Alternative Nomenclature

annexin 31 antibody

ANX31 antibody

ANXA9 antibody

Pemphaxin antibody

General Information

Product

Calpain Antibody

Description

Affinity Purified Calpain Schistosoma Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Reactivity

S. mansoni

Immunogen

Synthetic peptide taken within amino acid region 700-758 on Schistosoma mansoni Calpain protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot blot

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P27730

Overview

Calcium-activated non-lysosomal thiol-proteases.

Molecular Function

Calcium, Metal-binding.

Subcellular Location

Intracellular

Expression

Sporocysts and adult worms

Structure

Belongs to the peptidase C2 family; 1 Calpain catalytic domain; 2 EF-hand domains

Alternative Nomenclature

Calcium activated neutral proteinase 1 antibody

Calpain 1 (mu/I) large subunit antibody

CANP 1 antibody

Cell proliferation inducing protein 30 antibody

Micromolar Calpain antibody

Mu Calpain antibody

muCANP antibody

muCL antibody

General Information

Product

CACNB2 Antibody Affinity Purified

Description

Affinity Purified Voltage dependent L-type calcium channel subunit beta-2 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 500-600 on rat voltage-dependent L-type calcium channel subunit beta-2 protein

Accession #

NCBI: NP_446303

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8VGC3

Overview

The beta subunit of voltage-dependent calcium channel which contributes to calcium channel function by increasing peak calcium current, shifting the voltage dependencies fo activation and inactivation, modulating G-protein inhibition and controllin the alpha-1 subunit membrane targeting.

Molecular Function

Calcium; Transport; Ion transport

Subcellular Location

Cell membrane; Sacrolemma; Peripheral membrane protein, cytoplasmic side

Expression

Heart and brain.  Lower expression in lung.

Structure

L-type channel is composed of four subunits:  alpha-1, alpha-2, beta and gamma.

Alternative Nomenclature

AW060387 antibody

Ca(V) beta 2 antibody

CAB2 antibody

CAVB2 antibody

Cavbeta2 antibody

Cchb2 antibody

Lambert Eaton Myasthenic syndrome antigen antibody

MYSB antibody

General Information

Product

EDIL3 Antibody

Description

Affinity Purified EGF-like repeat and discoidin I-like domain-containg protein 3 isoform Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 30-60 on Del-1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.69-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500

Protein

Uniprot #

O35474

Overview

Promotes endothelial cells through interaction with the alpha-v/beta-3 integrin receptor.  Inhibits formation of vascular-like structures.

Molecular Function

Calcium, Metal-binding

Subcellular Location

Secreted

Expression

Angioblasts and early endothelial cells

Structure

Contains 3 EGF-like domains; Contains 3 F5/8 type C domains

Alternative Nomenclature

DEL1 antibody

Developmentally regulated endothelial cell locus 1 protein antibody

EGF like repeat and discoidin I like domain containing protein 3 antibody

Integrin-binding protein DEL1 antibody

General Information

Product

EHD2 Antibody

Description

Affinity Purified EH domain-containing protein 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse Rat

Immunogen

Synthetic peptide taken within amino acid 420-450 on human EH-Domain Containing Protein 2.

Accession #

NCBI:  NP_055416.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NZN4

Overview

Plays a role in membrane reorganization in response to nucleotide hydrolysis

Molecular Function

ATP binding; GTPase activity; nucleic acid binding; calcium ion binding; GTP binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.

Structure

Homodimer and homooligomer. Interacts with EHD1 and MYOF. May also interact with EHD3 and EHD4.

Alternative Nomenclature

EH domain containing 2 antibody

EH domain containing 3 antibody

EHD 2 antibody

EHD3 antibody

FLJ96617 antibody

PAST 2 antibody

General Information

Product

Cadherin 74A Antibody

Description

Affinity Purified Cadherin 74A, isoform A Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Synthetic peptide taken within amino acid region 100-150 on D. melanogaster Cadherin 74A, isoform A protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9VVG0

Molecular Function

Calcium ion binding; Protein homodimerization activity

Subcellular Location

Apical plasma membrane; Microvilus; Integral component of plasma membrane

Structure

Transmembrane helix

Alternative Nomenclature

Cadherin 74

Cadherin 74A

GD12413

GM24339

GG15818

GE22158

Cadherin-23-like

Cadherin 87A

General Information

Product

inaD Antibody

Description

Affinity Purified inactivation no afterpotential D, isoform A Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Fruity Fly (Drosophila melanogaster)

Immunogen

Synthetic peptide corresponding to C terminal amino acids 659-674 of Fruit fly (Drosophila melanogaster) inaD protein.

Sequence:

EVTRPKPTLRTEAPKA

Accession #

NCBI:  NP_726260.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q24008

Overview

Involved in the negative feedback regulation of the light-activated signaling cascade in photoreceptors through a calcium-mediated process.

Molecular Function

Calmodulin binding, myosin III binding, receptor signaling complex scaffold activity, structural molecule activity, myosin binding, photoreceptor activity

Subcellular Location

Cell membrane, preipheral membran protein

Expression

Expressed in rhabdomeres of the compound eyes and ocelli.

Alternative Nomenclature

Inactivation-no-after-potential D protein antibody

inaD antibody

General Information

Product

MRGX1 Antibody Affinity Purified

Description

Affinity Purified Mas-related G-protein coupled receptor member X1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 280-330 on rat MrgX1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.67 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8R4G1

Overview

Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors)

Structure

Belongs to the G-protein coupled receptor 1 family. Mas subfamily

Alternative Nomenclature

G protein coupled receptor MRGX1 antibody

G protein coupled receptor SNSR3 antibody

GPCR antibody

Mas related G protein coupled receptor member X1 antibody

MRGPRX1 antibody

MRGX1 antibody

Sensory neuron specific G protein coupled receptor 3/4 antibody

Seven transmembrane helix receptor antibody

SNSR3 antibody

SNSR4 antibody

General Information

Product

Phospho inaD Antibody Affinity Purified

Description

Affinity Purified Phospho Inactivation no afterpotential D, isoform A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Synthetic peptide taken within amino acid region 600-700 on iNAD protein.

Accession #

NCBI:  NP_726260.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500

Protein

Uniprot #

Q24008

Overview

Utilizes a calcium-mediated process to function in the negative feedback regulation of the light activated signalling cascade in photoreceptors.

Molecular Function

Calmodulin binding, myosin binding, photoreceptor activity

Subcellular Location

Cell membrane, Peripheral membrane protein

Expression

Expression is detected in rhabdomers of the compound eyes and ocelli

Structure

Interacts with the C-terminus of trp.  Forms the inaD signalling complex through its interaction  with norpA and inaC.

Alternative Nomenclature

Inactivation-no-after-potential D protein antibody

inaD antibody

INAD_DROME antibody