General Information |
|
Product |
FFAR3 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Free fatty acid receptor A3 Antibody |
Verified Applications |
ELISA, IP WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 270-320 on human FFAR3 protein. |
Specificity | This antibody will detect FFAR3. This antibody will not detect FFAR1, FFAR2, or FFAR4. |
Accession # |
NCBI: NP_005295.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.58-0.59 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins. Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation (PubMed:12711604). |
Molecular Function |
G-protein coupled receptor activity; Lipid binding |
Subcellular Location |
Cell Membrane; Multi-Pass Membrane Protein |
Expression |
Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia. |
Structure |
Belongs to the G-protein coupled receptor 1 family. |
Alternative Nomenclature |
FFA3R antibody Free fatty acid receptor 3 antibody G protein coupled receptor 41 antibody GPCR41 antibody GPR41 antibody gpr42 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
FFAR3-301AP | |||
|
P-FFAR3 | |||
|
FFAR3-BIOTIN | |||
|
PC-FFAR3 | |||
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