General Information |
|
Product |
MAPK3 Peptide |
Description |
Antigenic Blocking Peptide Mitogen-activated protein kinase 3 Antibody |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide taken within amino acid region 300-350 on human Mitogen-activated protein kinase 3. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. |
Molecular Function |
Kinase, Serine/threonine-protein kinase, Transferase |
Subcellular Location |
Cytoplasm, Nucleus |
Structure |
The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. |
Alternative Nomenclature |
Mitogen-activated protein kinase 3 Antibody MAP kinase 3 Antibody MAPK 3 Antibody ERT2 Antibody Extracellular signal-regulated kinase 1 Antibody ERK-1 Antibody Insulin-stimulated MAP2 kinase Antibody MAP kinase isoform p44 Antibody p44-MAPK Antibody Microtubule-associated protein 2 kinase Antibody p44-ERK1 Antibody MAPK3 Antibody ERK1 Antibody PRKM3 Antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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MAPK3-101AP | |||
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MAPK3-BIOTIN | |||
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MAPK3-FITC | |||
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PC-MAPK3 | |||
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