General Information
|
|
Product
|
Phospho PDE3B Antibody BIOTIN
|
Description
|
BIOTIN-Conjugated Phosphorylated Phosphodiesterase 3B Antibody N-epitope
|
Verified Applications
|
ELISA, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Chicken, Human, Monkey, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 260-310 on rat PDE3B protein. Selective for only PDE3B variant
|
Accession #
|
NCBI: EDM17772.1
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
1.0-1.25 µg/µl in antibody stabilization buffer
|
Form
|
BIOTIN-Conjugated
|
Clonality
|
Polyclonal
|
Determinant
|
N-epitope
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunoprecipitation
|
1:200
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
UPI000154F033
|
Overview
|
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3.
|
Molecular Function
|
Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
|
Subcellular Location
|
Membrane; Multipass membrane protein
|
Expression
|
Abundant in adipose tissues.
|
Structure
|
Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6 (By similarity).
|
Alternative Nomenclature
|
5''-cyclic phosphodiesterase B antibody
Adipocyte cAMP phosphodiesterase cGMP inhibited antibody
AI847709 antibody
cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody
CGI-PDE B antibody
CGIP1 antibody
CGIPDE1 antibody
cGMP inhibited 3 5 cyclic phosphodiesterase B antibody
HcGIP1 antibody
Pde3b antibody
Phosphodiesterase 3B cGMP inhibited antibody
|
|
|