General Information
|
|
Product
|
Relaxin 1 Antibody
|
Description
|
Affinity Purified Relaxin receptor 1 Antibody
|
Verified Applications
|
ELISA, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 100-150 on rat relaxin receptor 1 protein.
|
Accession #
|
NCBI: NP_958820
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
.5 µg/µl in antibody stabilization buffer
|
Immunoglobulin
|
IgG
|
Form
|
Affinity Purified
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunoprecipitation
|
1:150
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
Q6R6I6
|
Overview
|
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
|
Molecular Function
|
G-protein coupled receptor activity, metal ion binding; Adenylate cyclase-activating G-protein coupled receptor signaling pathway
|
Subcellular Location
|
Cell membrane; Multi-pass membrane protein
|
Expression
|
Detected in brain cortex, and at low levels in testis.
|
Structure
|
Belongs to the G-protein coupled receptor 1 family.
Contains 1 LDL-receptor class A domain.
Contains 11 LRR (leucine-rich) repeats.
|
Alternative Nomenclature
|
H1 antibody
H1RLX antibody
Preprorelaxin H1 antibody
Prorelaxin antibody
Prorelaxin H1 antibody
Relaxin 1 (H1) antibody
Relaxin A chain antibody
Relaxin1 antibody
RelaxinH1 antibody
RLN1 antibody
RLXH1 antibody
|
|
|