General Information |
|
Product |
PREX2 Antibody Western Blot Positive Control |
Description |
Western Blot Positive Control PtdIns(3,4,5)-dependent Rac exchanger 2a Antibody |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
GenBank: DAA05334.1 |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
|
|
Western Blot |
1:500-1:750 |
|
|
Uniprot # |
|
Overview |
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
Molecular Function |
Rac GTPase activator activity, Rac guanyl-nucleotide exchange factor activity |
Expression |
Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart. |
Alternative Nomenclature |
4 antibody 5)-dependent Rac exchanger 2 antibody 5-trisphosphate-dependent Rac exchanger 2 protein antibody DEP domain-containing protein 2 antibody DEP.2 antibody Phosphatidylinositol 3 antibody PtdIns(3,4,5)-dependent Rac exchanger 2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
PREX2-201AP | |||
|
PREX2-FITC | |||
|
P-PREX2 | |||
|
PREX2-BIOTIN | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.