General Information |
|
Product |
IFI16 Peptide |
Description |
Antigenic Blocking Peptide Gamma-interferon-inducible protein 16 isoform 1 |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide |
Accession # |
NCBI: NP_001193496.1 |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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|
Uniprot # |
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Overview |
Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. |
Molecular Function |
Core promoter binding, identical protein binding, transcription factor binding, double-standard DNA binding, poly(A) RNA binding |
Subcellular Location |
Nucleus, cytoplasm (Note: Cellular distribution is dependent on acetylation status of multipartite nuclear localization signal(NLS); NLS acetylation promotes cytoplasmic localization. Localizes in nucleus during human herbes simplex virus 1 infection) |
Expression |
Expressed in peripheral blood leukocytes, fibroblasts and lymphoid cells. Present in myeloid precursors (CD34+) and throughout monocyte development, but its expression is down-regulated in erythroid and polymorphonuclear precursor cells. Present in prosta |
Alternative Nomenclature |
IFI16 antibody Gamma interferon inducible protein 16 antibody Ifi204 antibody IFNGIP1 antibody interferon activated gene 204 antibody Interferon gamma inducible protein 16 antibody p204 antibody PYHIN2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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IFI16H-101AP | |||
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IFI16H-FITC | |||
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IFI16H-BIOTIN | |||
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PC-IFI16H | |||
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