General Information

Product

CXCR5 Antibody Affinity Purified

Description

Affinity Purified Chemokine (C-X-C motif) receptor 5 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 320-370 on human Chemokine (C-X-C motif) receptor 5 protein.

Accession #

Gen Bank: AAI10353.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q2YD84

Overview

Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Molecular Function

B-cell activation.

Subcellular Location

Integral component of plasma membrane; External side of plasma membrane

Expression

Expression in mature B-cells and Burkitt lymphoma cells

Structure

Belongs to the G-protein coupled receptor 1 family

Alternative Nomenclature

BLR 1 antibody

Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) antibody

C X C chemokine receptor type 5 antibody

CD 185 antibody

Chemokine receptor 5 antibody

CXC chemokine receptor type 5 antibody

CXCR-5 antibody

MDR 15 antibody

MGC117347 antibody

Monocyte-derived receptor 15 antibody

General Information

Product

LILRB3 Antibody

Description

Affinity Purified Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 580-631 on human LILRB3 protein.

Accession #

NCBI:  NP_001074919.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.74 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500

Protein

Uniprot #

O75022

Overview

May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).

Molecular Function

Receptor, Receptor activity, transmembrane signaling receptor activity

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Expression

Detected in monocytes and B-cells

Alternative Nomenclature

CD85 antigen like family member A antibody

HL9 antibody

IL T5 antibody

Immunoglobulin like transcript 5 antibody

LIR 3 antibody

MGC138403 antibody

Monocyte inhibitory receptor HL9 antibody

PIRB antibody

General Information

Product

LILRB3 Antibody

Description

Affinity Purified Leukocyte immunoglobulin-like receptor subfamily B member 3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse

Immunogen

Synthetic peptide taken within amino acid region 800-841 on mouse LILRB3 protein.

Accession #

NCBI:  NP_035225.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.74 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500

Protein

Uniprot #

P97484

Overview

May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).

Subcellular Location

Cell membrane, single-pass type I membrane protein

Expression

Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells.

Alternative Nomenclature

CD85 antigen like family member A antibody

HL9 antibody

IL T5 antibody

Immunoglobulin like transcript 5 antibody

LIR 3 antibody

MGC138403 antibody

Monocyte inhibitory receptor HL9 antibody

PIRB antibody

General Information

Product

Visfatin Antibody

Description

Affinity Purified Nicotinamide phosphoribosyltransferase precursor Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid region 200-300 on human Visfatin protein.

Accession #

NCBI:  NP_005737.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P43490

Overview

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma.

Molecular Function

Cytokine, Glycosyltransferase, Transferase

Subcellular Location

Nucleus, Cytoplasm, Secreted

Expression

Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.

Structure

Homodimer

Alternative Nomenclature

1110035O14Rik antibody

AI314458 antibody

AI480535 antibody

DKFZP666B131 antibody

EC 2.4.2.12 antibody

MGC117256 antibody

NAmPRTase antibody

Nampt antibody

Nicotinamide phosphoribosyltransferase antibody

PBEF antibody

PBEF1 antibody

Pre B cell colony enhancing factor antibody

Pre B cell enhancing factor antibody

VF antibody

Visfatin antibody

General Information

Product

Visfatin Antibody

Description

Affinity Purified Nicotinamide phosphoribosyltransferase precursor Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

C-epitope synthetic peptide taken within amino acid region 400-490 on human Visfatin protein.

Accession #

NCBI:  NP_005737.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P43490

Overview

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma.

Molecular Function

Cytokine, Glycosyltransferase, Transferase

Subcellular Location

Nucleus, Cytoplasm, Secreted

Expression

Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.

Structure

Homodimer

Alternative Nomenclature

1110035O14Rik antibody

AI314458 antibody

AI480535 antibody

DKFZP666B131 antibody

EC 2.4.2.12 antibody

MGC117256 antibody

NAmPRTase antibody

Nampt antibody

Nicotinamide phosphoribosyltransferase antibody

PBEF antibody

PBEF1 antibody

Pre B cell colony enhancing factor antibody

Pre B cell enhancing factor antibody

VF antibody

Visfatin antibody

General Information

Product

BST2 Antibody

Description

Affinity Purified Bonemarrow stromal antigen 2 Antibody N-epitope

Verified Applications

ELISA, CM, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

N-epitope Synthetic peptide taken within amino acid region 1-50 on human Bonemarrow stromal antigen 2 protein.

Accession #

GenBank:  BAD96844

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:2,000

ELISA

1:2,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q10589

Overview

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.

Molecular Function

Antiviral defense; B-cell activation; Immunity; Innate immunity

Subcellular Location

Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane

Expression

Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.

Structure

Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.

Alternative Nomenclature

Bone marrow stromal antigen 2 antibody

Bone marrow stromal cell antigen 2 antibody

BST 2 antibody

CD 317 antibody

CD317 antigen antibody

HM1.24 antigen antibody

NPC A 7 antibody

Tetherin antibody

General Information

Product

BST2 Antibody

Description

Affinity Purified Bonemarrow stromal antigen 2 Antibody Mid-Region

Verified Applications

ELISA, CM, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Mid-Region Epitope Synthetic peptide taken within amino acid region 50-100 on human Bonemarrow stromal antigen 2 protein.

Accession #

GenBank:  BAD96844

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:2,000

ELISA

1:2,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q10589

Overview

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.

Molecular Function

Antiviral defense; B-cell activation; Immunity; Innate immunity

Subcellular Location

Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane

Expression

Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.

Structure

Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.

Alternative Nomenclature

Bone marrow stromal antigen 2 antibody

Bone marrow stromal cell antigen 2 antibody

BST 2 antibody

CD 317 antibody

CD317 antigen antibody

HM1.24 antigen antibody

NPC A 7 antibody

Tetherin antibody

General Information

Product

BST2 Antibody

Description

Affinity Purified Bonemarrow stromal antigen 2 Antibody C-epitope

Verified Applications

ELISA, CM, ICC, IF, IHC, IP, WB

Host

Rabbit

Immunogen

C-epitope Synthetic peptide taken within amino acid region 100-150 on human Bonemarrow stromal antigen 2 protein.

Accession #

GenBank:  BAD96844

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DOT Blot

1:2,000

ELISA

1:2,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q10589

Overview

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.

Molecular Function

Antiviral defense; B-cell activation; Immunity; Innate immunity

Subcellular Location

Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane

Expression

Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.

Structure

Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.

Alternative Nomenclature

Bone marrow stromal antigen 2 antibody

Bone marrow stromal cell antigen 2 antibody

BST 2 antibody

CD 317 antibody

CD317 antigen antibody

HM1.24 antigen antibody

NPC A 7 antibody

Tetherin antibody

General Information

Product

PrLZ / TPD52 Antibody

Description

Affinity Purified Prostate leucine zipper isoform 5 Antibody Mid-Region

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 20-70 on human Prostate leucine zipper isoform 5 protein.

Accession #

NCBI:  NP_001020423.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.69 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

P55327

Molecular Function

calcium ion binding, protein heterodimerization activity, protein homodimerization activity

Subcellular Location

cytoplasm, perinuclear region of cytoplasm, endoplasmic reticulum

Expression

Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver

Structure

Forms a homodimer or heterodimer with other members of the family. All isoforms interact with several 14-3-3 proteins.

Alternative Nomenclature

D52 antibody

Human 19.8 kDa protein mRNA, complete cds antibody

N8L antibody

PC 1 antibody

PC1/MRPS28 fusion protein antibody

PrLZ antibody

Prostate and colon associated protein antibody

Prostate leucine zipper antibody

Protein N8 antibody

TPD52 antibody

Tumor protein D52 antibody

General Information

Product

PrLZ / TPD52 Antibody

Description

Affinity Purified Prostate leucine zipper isoform 5 Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 101-151 on human Prostate leucine zipper isoform 5 protein.

Accession #

NCBI:  NP_001020423.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.69 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

P55327

Molecular Function

calcium ion binding, protein heterodimerization activity, protein homodimerization activity

Subcellular Location

cytoplasm, perinuclear region of cytoplasm, endoplasmic reticulum

Expression

Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and at very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary.

Structure

Forms a homodimer or heterodimer with other members of the family. All isoforms interact with several 14-3-3 proteins.

Alternative Nomenclature

D52 antibody

Human 19.8 kDa protein mRNA, complete cds antibody

N8L antibody

PC 1 antibody

PC1/MRPS28 fusion protein antibody

PrLZ antibody

Prostate and colon associated protein antibody

Prostate leucine zipper antibody

Protein N8 antibody

TPD52 antibody

Tumor protein D52 antibody