General Information
|
|
Product
|
Netrin 1 Antibody BIOTIN-Conjugated
|
Verified Applications
|
ELISA, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 250-300 on human Netrin-1 protein.
|
Accession #
|
NCBI: NP_004813.2
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.62-0.68 µg/µl in antibody stabilization buffer
|
Form
|
BIOTIN-Conjugated
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunoprecipitation |
1:200 |
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
O95631
|
Overview
|
Netrins control guidance of CNS commissural axons and peripheral motor axons; serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis;Involved in tumorigenesis by regulating apoptosis.
|
Subcellular Location
|
Extracellular matrix, Secreted
|
Expression
|
highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. Expressed in epididymis (at protein level).
|
Alternative Nomenclature
|
epididymis tissue protein Li 131P antibody
Netrin 1, mouse, homolog of antibody
Netrin 1-like antibody
Ntn 1 antibody
Unc6 antibody
|
|
|