General Information |
|
Product |
ASF1A Positive Control |
Description |
Western Blot Positive Control Histone Chaperone ASF1A Antibody |
Verified Applications |
WB |
Immunogen |
Purified Protein |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. |
Molecular Function |
Transcription regulation |
Subcellular Location |
Nucleus |
Structure |
Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with CABIN1, HAT1, HIRA, NASP, TAF1, TLK1, TLK2 and UBN1. Interacts with CDAN1. Found in cytosolic coplex with CDAN1, ASF1B, IPO4 and histones H3.1 and H4. Interacts with CREBBP. |
Alternative Nomenclature |
Anti silencing function 1A antibody asf1a antibody CCG1-interacting factor A antibody CGI 98 antibody CIA antibody hAsf1 antibody hAsf1a antibody hCIA antibody Histone chaperone ASF1A antibody HSPC146 antibody Hypothetical protein FLJ22085 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
ASF1A-101AP | |||
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ASF1A-FITC | |||
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P-ASF1A | |||
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ASF1A-BIOTIN | |||
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